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  Phenylephrine HCL 10mg/1ml
  Indications :
 

Blood pressure maintenance:
- Severe hypotension and shock

- Spinal anesthesia

- Prolongation of spinal anesthesia

- Vasoconstrictor for regional anesthesia

- Paroxysmal supraventricular tachycardia

   
  Dosage :
  Mild or moderate hypotension :
SC or IM –
The usual dose is from 2 to 5mg (initial dose should not exceed 5mg.

IV - The usual dose is 0.2mg. Initial dose should not exceed 0.5mg

Severe hypotension and shock :
Continuous infusion – Add 10 mg of the drug to 500ml of dextrose injection or sodium chloride injection. To raise the blood pressure rapidly start the infusion at about 100mcg to 180mcg/min.When the blood pressure is normalized, a maintenance rate of 40-60mcg/min usually suffices.

Spinal anesthesia :
SC or IM 3 or 4 minutes before injection of the spinal anesthetic .The total requirement for high anesthetic levels is usually 3mg and for lower levels 2mg. For hypotensive emergencies during spinal anesthesia phenylephrine may be injected IV, using an initial dose of 0.2mg Any subsequent dose should not exceed the previous dose by more than 0.1 to 0.2mg and no more than 0.5mg should be administered in a single dose.

Prolongation of spinal anesthesia :
The addition of 2 to 5mg of phenylephrine of to the anesthetic solution increases the duration of motor block by as much as approx.50%.

Vasoconstrictor for regional anesthesia :
Conc. About 10 times those employed when epinephrine is used as a vasoconstrictor are recommended .The optimum strength is 1:20000(made by adding 1mg of phenyephrine to every 20ml of local anesthetic solution).

Paroxysmal supraventricular tachycardia :
Rapid IV injection (within 20-30sec) is recommended. The initial dose should not exceed 0.5mg and subsequent doses which re determined by the initial blood pressure, should not exceed the preceeding dose by more than 0.1-0.2mg and should never exceed 1mg
   
  Packing : 1 Amp. of 10mg/1ml
 



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