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Pamidronate Disodium for IV Infusion BP 60 mg |
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Hypercalcemia of Malignancy (Moderate to Severe)
Paget's Disease
Osteolytic Bone Metastases of Breast Cancer
Osteolytic Lesions of Multiple Myeloma
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Moderate Hypercalcemia (serum calcium 12-13.5 mg/dL) : 60 to 90 mg given as a single-dose, intravenous infusion over 2 to 24 hours.
Severe Hypercalcemia (serum calcium >13.5 mg/dL) : 90 mg given as a single-dose, intravenous infusion over 2 to 24 hours.
Paget's Disease (Moderate to Severe ) : 30 mg daily, administered as a 4-hour infusion on 3 consecutive days for a total dose of 90 mg.
Osteolytic Lesions of Multiple Myeloma : 90 mg administered as a 4-hour infusion given on a monthly basis.
Osteolytic Bone Metastases of Breast Cancer : 90 mg administered over a 2-hour infusion given every 3-4 weeks.
Dosage Adjustment :
Renal Impairment : Required.
Hepatic Impairment : Not well studied, administer with caution. |
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Packing : |
5 Vials of 60 mg/Vial |
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