Adult : 0.5 to 1 g daily in divided doses.
15 to 20 mg/kg (given as a single daily dose, up to maximum of 1 g.
Children : 12 to 15 mg/kg body weight daily to a maximum of 750 mg daily in divided doses.
Some children have received 20 mg/kg daily.
15 to 20 mg/kg (given as a single daily dose).
Renally Impaired Patients : Dosage should be reduced to 250–500 mg daily in
patients with creatinine clearance less than
30 mL/minute and in those undergoing hemodialys. |