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Epirubicin Hydrochloride for Injection 10 mg |
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Breast Cancer
Ovarian Cancer
Gastric Cancer
Lung Cancer
Lymphomas
Bladder Cancer
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Epirubicin is given in repeated 3 to 4 week cycles.
The total dose of Epirubicin may be given on Day 1 of each cycle or divided equally and given on Days 1 and 8 of each cycle. The recommended dosages of Epirubicin are as follows :
Starting Doses : The recommended starting dose of Epirubicin is 100 to 120 mg/m2. The following regimens were used in the trials supporting use of Epirubicin as a component of adjuvant therapy in patients with axillary-node positive breast cancer;
CEF-120 : Cyclophosphamide-75 mg/m2 PO Day 1-14 Epirubicin- 60 mg/m2 IV Day 1, 8 5-Fluorouracil -500 mg/m2 IV Day 1, 8 Repeated every 28 days for 6 cycles
FEC-100 : 5-Fluorouracil- 500 mg/m2, Epirubicin- 100 mg/m2, Cyclophosphamide- 500 mg/m2
Dosage Adjustment :
Renal Impairment :Administer with caution.
Hepatic Impairment : Required. |
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Packing : |
5 Vials of 10 mg |
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