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  Capecitabine Tablets USP 500 mg
  Indications :
 

Adjuvant in colorectal cancer Stage III Dukes' C - used as first-line monotherapy.

Metastatic colorectal cancer - used as first-line monotherapy, if appropriate.

Metastatic breast cancer - used in combination with docetaxel, after failure of anthracycline-based treatment.

Route of Administration : for oral use only

   
  Dosage :
  The usual starting dose is 2,500 mg/m2/day in two divided doses, 12 hours apart. One cycle includes two weeks of treatment followed by one week without treatment. Cycles can be repeated every three weeks.

Dose Adjustments

Renal Impairment :
Required.

Hepatic Dysfunction : In patients with mild to moderate hepatic dysfunction due to liver metastases, no starting dose adjustment is necessary; however, patients should be carefully monitored. Patients with severe hepatic dysfunction have not been studied.
   
  Packing : 5 Strips of 10 Tablets
 



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