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As an adjunct in the prevention of rejection in renal and solid organ transplantation.
Management of severe rheumatoid arthritis.
Autoimmune diseases :
- Inflammatory bowel disease including moderate to severe crohn's disease.
- Autoimmune hepatitis.
- Systemic lupus erythematosus.
- Multiple sclerosis.
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Renal and solid organ transplantation :
Children and adults : 2-5 mg/kg/day to start at the time of transplant, then 1-3 mg/kg/day as a maintenance dose.
Rheumatoid arthritis and autoimmune disease :
Adults :
Initial : 1 mg/kg/day given once daily or divided twice daily 6-8 weeks; increase by 05 mg/kg every 4 weeks until response or up to 2.5 mg/kg/day.
Maintenance dose : Reduce dose by 0.5 mg/kg every 4 weeks unitl lowest effective dose is reached.
Dosage Adjustment :
Renal Impairment : Require adjustment.
Hepatic Impairment : Administer with caution. |
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Packing : |
10 Strips of 10 Tablets |
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