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Amphotericin-B for Injection USP 50 mg |
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Fungal endocarditis
Meningitis
Peritonitis
Severe respiratory tract infections
Fungal infections such as Aspergillosis, Candidiasis etc
Blastomycosis
Histoplasmosis
Cryptococosis
Visceral Leishmaniasis
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Initial Dose : Therapy is usually initiated with a daily dose of 0.25mg/kg of body weight given over 2 to 6 hours.
Systemic candidiasis : Usual doses ranging from 0.4 to 0.6 mg/kg/day for 4 or more weeks. Doses up to 1 mg/kg/day may need to be employed depending upon the severity of the infection.
Aspergillosis : Doses of 0.5 to 1 mg/kg/day or more & cumulative doses of 2 to 4 g in adults may be required for serious infections.
Blastomycosis : In seriously ill patients with blastomycosis, doses ranging from 0.3 to 1 mg/kg/day to a total cumulative dose of 1.5 to 2.5 g.
Cryptococcosis : Doses of 0.3 mg/kg/day for periods approximating
(Cryptococcosis in non 4 to 6 weeks or until weekly cultures are negative
immunosuppressed for one month
patients).
Histoplasmosis : Doses approx. 0.5 to 1 mg/kg/day to a total cumulative
(Chronic pulmonary dose of 2 to 2.5 g.
or disseminated
histoplasmosis).
Usual Pediatric Dose : 100 -250 mcg /kg body weight.
Renally Impaired Patients : Depending on the patient's cardio-renal status doses may gradually be increased by 5 to 10 mg per day to final daily dosage of 0.5 to 0.7 mg/kg. |
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Packing : |
10 Vials of 50 mg |
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